贾明玺，讲师，硕士生导师
电子信箱：JIAMXdream@163.com
研究领域：天然产物精深加工与功能活性评价
个人简介：长期聚焦天然活性物质的提取、改性及功能强化研究，尤其在微胶囊化、纳米载体递送系统开发及天然产物活性机理领域积累了扎实的理论基础与实践经验。负责和参与3项省级项目，近年来在Food & Function, Critical Reviews in Food Science and Nutrition, International Journal of Pharmaceutics, Molecular Carcinogenesis和Environmental Pollution等国际学术杂志发表多篇论文，涵盖纳米乳液、多孔载体及天然产物活性机制等方向，其中以第一作者和通讯作者发表SCI论文9篇。
一、学习经历
2012年9月至2016年6月，新乡医学院，生物医学工程，学士；
2016年9月至2019年6月，湖南工业大学，生物医学工程，硕士；
2020年9月至2024年6月，中南林业科技大学，食品科学与工程，博士。
二、工作经历
2019年7月至2020年9月，北京吉因加科技有限公司基因研究院，新技术开发员；
2024年9月至今，新疆农业大学食品科学与药学学院，教师。
三、近5年主持的科研项目
[1] 新疆维吾尔自治区“天池英才”项目，“葡萄废渣中二十八烷醇的提取、纳米封装及其抗肿瘤作用的研究”，主持，2025.01-2027.12；
[2] 自治区青年科学基金项目，“膳食二十八烷醇靶向MMPs调控动脉粥样硬化斑块稳定性机制研究”，主持，2025.09-2028.09。
四、近5年发表的文章
[1] Mingxi Jia, Wenjing Zhang, Taojin He, Meng Shu, Jing Deng, Jianhui Wang, Wen Li*, Jie Bai*. Evaluation of the Genotoxic and Oxidative Damage Potential of Silver Nanoparticles in Human NCM460 and HCT116 Cells. International Journal of Molecular Sciences. 2020, 21, 1618.
[2] MingXi Jia, JinTao He, WeiDong Bai, QinLu Lin, Jing Deng*, Wen Li*. Cross-Kingdom Regulation by Dietary Plant miRNAs: An Evidence-Based Review with Recent Updates. Food & Function. 2021,12, 9549-9562.
[3] MingXi Jia, WeiDong Bai, Jing Deng, Wen Li*, QinLu Lin. Enhancing Solubility and Bioavailability of Octacosanol: Development of a Green O/W Nanoemulsion Synthesis Process. International Journal of Pharmaceutics. 2024,651,123726.
[4] JinTao He+, MingXi Jia+, Wen Li*, Jing Deng, JiaLi Ren, FeiJun Luo. Toward improvements for enhancement the productivity and color value of Monascus pigments: a critical review with recent updates. Critical Reviews in Food Science and Nutrition. 2021, 10, 1-15.
[5] Xishan Zhou, Guofeng Liu, Mo Xu, Xintao Ying, Bianfeng Li, Fengxi Cao, Mingxi Jia*, Wen Li*. Comprehensive analysis of PTEN‐related ceRNA network revealing the key pathways WDFY3‐AS2 ‐ miR‐21‐5p/miR‐221‐3p/miR‐222‐3p ‐ TIMP3 as potential biomarker in tumorigenesis and prognosis of kidney renal clear cell carcinoma. Molecular Carcinogenesis. 2022, 61(5), 508-523.
[6] Mingxi Jia, Shanshan Feng, Fengxi Cao, Jing Deng*, Wen Li*, Wangyan Zhou, Xiang Liu, Weidong Bai. Identification of EGFR-Related LINC00460/mir-338-3p/MCM4 Regulatory Axis as Diagnostic and Prognostic Biomarker of Lung Adenocarcinoma Based on Comprehensive Bioinformatics Analysis and Experimental Validation. Cancers. 2022,14(20), 5073.
[7] Mingxi Jia, Yi Shi, Yang Xie, Wen Li*, Jing Deng, Da Fu. WT1-AS/IGF2BP2 Axis Is a Potential Diagnostic and Prognostic Biomarker for Lung Adenocarcinoma According to ceRNA Network Comprehensive Analysis Combined with Experiments. Cells. 2022, 11(1), 25.
[8] MingXi Jia, Yi Shi, Jing Deng, Wen Li, QinLu Lin, Da Fu, FeiJun Luo, Jie Bai, Kilaza Samson Mwaikono. Octacosanol inhibits tumor metastasis and invasion by targeting MMPs via PI3K/AKT and MAPK signaling pathways. Journal of Agriculture and Food Research. 2025, 24, 102464.
[9] Zhigang Xiao, Mingchuan Zheng, Jing Deng, Yi Shi, Mingxi Jia*, Wen Li*. Nano-TiO2 regulates the MAPK (ERK, P38) pathway to promote apoptosis and inhibit proliferation of human colon cells. Ecotoxicology and Environmental Safety. 2024,283:116973.
[10] Haixia Han, Juanjuan Gao, Quan Sun, Dandan Tong, Jian Liu, Zuoshan Feng, Mingxi Jia*.Coreopsis tinctoria Nutt. Polyphenols Attenuates Acrylamide-Induced Cerebral Injury via Dual Modulation of Nrf2/HO-1 and MAPK Pathways. Journal of the Science of Food and Agriculture.
五、主讲课程
《药剂学》《药学分子生物学》《药理学实验》
